ChemicalBook--->CAS DataBase List--->66056-22-2

66056-22-2

66056-22-2 Structure

66056-22-2 Structure
IdentificationBack Directory
[Name]

Angeloylgomisin H
[CAS]

66056-22-2
[Synonyms]

Angeloylgomisin H
(2Z)-2-Methyl-2-butenoic acid (6S,7S,12aR)-5,6,7,8-tetrahydro-7-hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-1-yl ester
2-Butenoic acid, 2-methyl-, (6S,7S,12aR)-5,6,7,8-tetrahydro-7-hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-1-yl ester, (2Z)-
[Molecular Formula]

C28H36O8
[MDL Number]

MFCD29904527
[MOL File]

66056-22-2.mol
[Molecular Weight]

500.58
Chemical PropertiesBack Directory
[Boiling point ]

656.3±55.0 °C(Predicted)
[density ]

1.144±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

14.56±0.40(Predicted)
[color ]

White to off-white
[biological source]

plant
[Major Application]

metabolomics
vitamins, nutraceuticals, and natural products
[InChI]

1S/C28H36O8/c1-10-15(2)27(29)36-26-21-17(12-19(31-5)24(26)34-8)11-16(3)28(4,30)14-18-13-20(32-6)23(33-7)25(35-9)22(18)21/h10,12-13,16,30H,11,14H2,1-9H3
[InChIKey]

ZSAUXCVJDYCLRS-UHFFFAOYSA-N
[SMILES]

OC1(C(Cc2c(c(c(c(c2)OC)OC)OC(=O)C(=CC)C)c3c(cc(c(c3OC)OC)OC)C1)C)C
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Schisandra chinensis.
[Uses]

Angeloylgomisin H is a bioactive lignan present in Schisandra chinensis fructus and has been shown to display antihepatotoxic and or antihyperlipidemic activity.
[Definition]

ChEBI: Angeloylgomisin h is a tannin.
[Biological Activity]

  • Inhibits the activity of enzymes involved in carcinogenic metabolismsuch as ornithine decarboxylase and acetylcholinesterase.
  • Facilitates the detoxification of specific carcinogensincluding benzo(a)pyreneby converting them into non-toxic metabolites.
  • Exhibits anti-diabetic effectspotentially linked to its capacity to stimulate insulin release.

[IC 50]

PPAR-γ
Spectrum DetailBack Directory
[Spectrum Detail]

Angeloylgomisin H(66056-22-2)1HNMR
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