| Identification | Back Directory | [Name]
Angeloylgomisin H | [CAS]
66056-22-2 | [Synonyms]
Angeloylgomisin H
(2Z)-2-Methyl-2-butenoic acid (6S,7S,12aR)-5,6,7,8-tetrahydro-7-hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-1-yl ester
2-Butenoic acid, 2-methyl-, (6S,7S,12aR)-5,6,7,8-tetrahydro-7-hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-1-yl ester, (2Z)- | [Molecular Formula]
C28H36O8 | [MDL Number]
MFCD29904527 | [MOL File]
66056-22-2.mol | [Molecular Weight]
500.58 |
| Chemical Properties | Back Directory | [Boiling point ]
656.3±55.0 °C(Predicted) | [density ]
1.144±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
14.56±0.40(Predicted) | [color ]
White to off-white | [biological source]
plant |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Schisandra chinensis. | [Uses]
Angeloylgomisin H is a bioactive lignan present in Schisandra chinensis fructus and has been shown to display antihepatotoxic and or antihyperlipidemic activity. | [Definition]
ChEBI: Angeloylgomisin h is a tannin. | [Biological Activity]
- Inhibits the activity of enzymes involved in carcinogenic metabolismsuch as ornithine decarboxylase and acetylcholinesterase.
- Facilitates the detoxification of specific carcinogensincluding benzo(a)pyreneby converting them into non-toxic metabolites.
- Exhibits anti-diabetic effectspotentially linked to its capacity to stimulate insulin release.
| [IC 50]
PPAR-γ |
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