| Chemical Properties | Back Directory | [Melting point ]
165-167 °C(Solv: chloroform (67-66-3); methanol (67-56-1); ethyl acetate (141-78-6)) | [Boiling point ]
489.8±25.0 °C(Predicted) | [density ]
0.984±0.06 g/cm3(Predicted) |
| Hazard Information | Back Directory | [Uses]
Glochidone is an anti-cancer agent with IC50s of 5.52 μM and 7.84 μM against HOP-62 and EPLC-272H cells, respectively[1]. | [Definition]
ChEBI: Glochidone is a pentacyclic triterpenoid that is lupa-1,20(29)-diene substituted by an oxo group at position 3. It has been isolated from Breynia fruticosa. It has a role as a plant metabolite. It is a pentacyclic triterpenoid and a cyclic terpene ketone. It derives from a hydride of a lupane. | [References]
[1] Chen H, et al. Glochidiol, a natural triterpenoid, exerts its anti-cancer effects by targeting the colchicine binding site of tubulin. Invest New Drugs. 2021 Apr;39(2):578-586. DOI:10.1007/s10637-020-01013-1 |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
|