| Identification | Back Directory | [Name]
6-Chloropyridazine-3-carboxamide | [CAS]
66346-83-6 | [Synonyms]
CML-035
6-Chloropyridazine-3-carboxamide
3-Chloro-pyridazine-6-carboxamide
3-PyridazinecarboxaMide, 6-chloro-
6-Chloropyridazine-3-carboxamide 97%
6-Chloropyridazine-3-carboxamide ISO 9001：2015 REACH
3-Carbamoyl-6-chloropyridazine, 3-(Aminocarbonyl)-6-chloro-1,2-diazine | [Molecular Formula]
C5H4ClN3O | [MDL Number]
MFCD09258882 | [MOL File]
66346-83-6.mol | [Molecular Weight]
157.56 |
| Chemical Properties | Back Directory | [Melting point ]
232-234 °C(Solv: water (7732-18-5)) | [Boiling point ]
424.6±30.0 °C(Predicted) | [density ]
1.478±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
solid | [pka]
13.62±0.50(Predicted) | [color ]
Off-white |
| Hazard Information | Back Directory | [Synthesis]
1. An excess of gaseous ammonia was slowly passed into a solution of n-butyl 6-chloropyridazine-3-carboxylate (40 g) in methanol (280 ml) in an ice bath. 2. The reaction mixture was stirred at room temperature for 4 h. 3. Upon completion of the reaction, the solid product was collected by filtration and washed with methanol (20 ml). 4. Drying gave 6-chloropyridazine-3-carboxamide (28.05 g, yield 95.5%) with a melting point of 243-245°C. 5. NMR hydrogen spectroscopy (DMSO-d6) data: δ 7.96 (broad peak, 1H), 8.07 (double peak, 1H, J = 8.3 Hz), 8.22 (double peak, 1H, J = 8.3 Hz), 8.52 (broad peak, 1H). 6-Chloropyridazine-3-carboxamide was dried. | [References]
[1] Patent: US6100258, 2000, A
[2] Patent: US5843942, 1998, A |
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