663599-10-8

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663599-10-8 Structure

Identification	Back Directory
[Name] 2,5-Dioxopyrrolidin-1-yl 4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoate
[CAS] 663599-10-8
[Synonyms] DMAC-SPP 2,5-Dioxopyrrolidin-1-yl 4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoate
[Molecular Formula] C17H21N3O5S2
[MDL Number] MFCD20227697
[MOL File] 663599-10-8.mol
[Molecular Weight] 411.5

Hazard Information	Back Directory
[Uses] DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50] Disulfide Cleavable Linker; Cleavable Linker
[References] [1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

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