| Identification | Back Directory | [Name]
GLYCOPROTEIN, ALPHA1-ACID HUMAN | [CAS]
66455-27-4 | [Synonyms]
AGP
PSK1
TAO1
ps-k
PSKR
SEZ6L2
MAP3K17
OROSOMUCOID
C-AGP, HUMAN
PSK (Kureha)
UNQ1903/PRO4349
FromBovineserum
Phytosulfokine-α
ALPHA1-AG, HUMAN
OROSOMUCOID HUMAN
OROSOMUCOID SHEEP
AGP, Orosomucoid
OROSOMUCOID BOVINE
α-Acid Glycoprotein
Seizure 6-like protein 2
ALPHA1-ACID GLYCOPROTEIN
alpha1-glycoprotein acid
ALPHA-1-SEROMUCOID, HUMAN
GLYCOPROTEIN, ALPHA1-ACID
GLYCOPROTEIN, A1-ACID RAT
alpha-1-Glycoproteineacid
ALPHA1 M-SEROMUCOID, HUMAN
GLYCOPROTEIN, A1-ACID SHEEP
GLYCOPROTEIN, A1-ACID HUMAN
GLYCOPROTEIN, A1-ACID BOVINE
GLYCOPROTEIN A1-ACID BABOON
ALPHA1-ACID GLYCOPROTEIN, HUMAN
GLYCOPROTEIN, ALPHA1-ACID HUMAN
GLYCOPROTEIN, ALPHA1-ACID SHEEP
ALPHA-1 ACID GLYCOPROTEIN PLASMA
GLYCOPROTEIN, ALPHA1-ACID BOVINE
α1-Acid Glycoprotein from rat
α?-Acid Glycoprotein, Human Plasma
a1-Acid glycoprotein (orosomuncoid)
ALPHA1-ACID GLYCOPROTEIN, HUMAN SERUM
ALPHA1-ACID GLYCOPROTEIN (OROSOMUCOID)
α1-acid glycoprotein from human plasma
α1-acid glycoprotein from sheep plasma
α1-acid glycoprotein from baboon plasma
α1-acid glycoprotein from bovine plasma
TAOK2 (1-314), active, GST tagged human
GLYCOPROTEIN, ALPHA1-ACID HUMAN USP/EP/BP
ALPHA(1)-GLYCOPROTEIN ACID FROM BOVINE SERUM*
ANTI-SE6L2 (C-TERM) antibody produced in rabbit
α1-Acid Glycoprotein from sheep plasma,Orosomucoid
α1-Acid Glycoprotein from bovine plasma,Orosomucoid
α1-Acid Glycoprotein from human plasma,AGP, Orosomucoid
ALPHA(1)-ACID GLYCOPROTEIN FROM HUMAN PL ASMA, FRACTION VI | [Molecular Formula]
NULL | [MDL Number]
MFCD00131224 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
H2O: 10 mg/mL, clear, colorless | [form ]
Lyophilized | [biological source]
human plasma | [Merck ]
13,8018 | [Specific Activity]
88-120nmol/min·mg |
| Hazard Information | Back Directory | [Chemical Properties]
This product is a brown or brownish powder with a slight characteristic odor and is odorless. The melting point is 120°C. It is soluble in water but virtually insoluble in methanol, chloroform, benzene, cyclohexane, etc.
This product is a proteoglycan with a protein content of 25%-30%. It exhibits anti-tumor activity both in vivo and in vitro. Its anti-tumor effect is related to its ability to stimulate the body's anti-tumor immune function. Yunzhi polysaccharide can enhance cellular immunity and promote delayed-type hypersensitivity reactions and lymphocyte proliferation. It can also increase the production of interferon, interleukin 1 and 2, and prostaglandins. It can also restore low IgG and IgM levels in tumor-bearing animals to normal. However, it does not enhance the phagocytic function of macrophages in tumor-bearing animals.
After oral administration, Yunzhi polysaccharide is absorbed from the digestive tract and distributed throughout organs and tumor tissues. Approximately 70% is eliminated from the body within 24 hours, primarily through the respiratory tract in the form of carbon dioxide. | [Uses]
GLYCOPROTEIN, ALPHA1-ACID HUMAN was used to study nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimine.
| [Uses]
α1-Acid glycoprotein from human plasma has been used:
- as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayers
- to incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISA
- to study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors
| [General Description]
α-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family. | [Biochem/physiol Actions]
α1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital. | [Purification Methods]
Purify the glycoprotein 1 acid by passage through a carboxymethyl cellulose column, then through a Sephadex G-25 column. [Aronson et al. J Biol Chem 243 4564 1968.] |
|
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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Alfa Chemistry
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https://www.alfa-chemistry.com |
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