| Identification | Back Directory | [Name]
1-(3-beta-Azido-2,3-dideoxy-5-O-trityl-beta-D-threopenta-furanosyl)thyMine | [CAS]
66503-47-7 | [Synonyms]
3’-β-Azido-3’-deoxy-5’-O-trityl thymidine
3'-beta-Azido-3'-deoxy-5'-O-trityl thyMidine
1-(3-b-Azido-2,3-dideoxy-5-O-trityl-b-D-threopenta furanosyl) thymine
1-(3-beta-Azido-2,3-dideoxy-5-O-trityl-beta-D-threopenta-furanosyl)thyMine
1-[3'-azido-2',3'-dideoxy-5'-(triphenylmethyl)-β-D-threo-pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione
1-[3-Azido-2,3-dideoxy-5-O-(triphenylmethyl)-beta-D-threo-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione | [Molecular Formula]
C29H27N5O4 | [MOL File]
66503-47-7.mol | [Molecular Weight]
509.556 |
| Hazard Information | Back Directory | [Uses]
1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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