| Identification | Back Directory | [Name]
Tsugafolin | [CAS]
66568-97-6 | [Synonyms]
Tsugafolin
7-Hydroxy-5,4'-dimethoxyflavanone
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-(4-methoxyphenyl)-, (2S)- | [Molecular Formula]
C17H16O5 | [MDL Number]
MFCD26406139 | [MOL File]
66568-97-6.mol | [Molecular Weight]
300.31 |
| Chemical Properties | Back Directory | [Boiling point ]
524.446±50.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.281±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
7.341±0.40(predicted) |
| Hazard Information | Back Directory | [Description]
Tsugafolin has weak anti-HIV activity. | [Uses]
Tsugafolin (compound 4) is a dehydroflavone with weak anti-HIV activity (IC50=118 μM) and devoid cytotoxicity (<150 μM). Tsugafolin can be isolated from Vitex leptobotrys[1]. | [target]
HIV | [References]
[1] Tanaka R, et al. A new flavanone derivative from the leaves of Tsuga diversifolia[J]. Planta medica, 1989, 55(06): 570-571. |
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