| | Identification | Back Directory |  | [Name] 
 POBN
 |  | [CAS] 
 66893-81-0
 |  | [Synonyms] 
 POBN
 Butylpyridyloxidenitrone
 -(4-pyridyl-1-oxide)nitrone
 N-tert-Butyl-&alpha
 4-Pyridyl-1-oxide-tert-butyl Nitrone
 N-TERT-BUTYL-A-(4-PYRIDYL)NITRONEN-OXIDE
 A-(4-PYRIDYL-N-OXIDE-N-TERT-BUTYLNITRONE
 α-(4-pyridyl n-oxide)-n-tert-butylnitrone
 N-tert-Butyl-α-(4-pyridyl-1-oxide)nitrone
 N-tert-Butyl-α-(4-pyridyl)nitrone Nμ-oxide
 ALPHA-(4-PYRIDYL-1-OXIDE)-N-T-BUTYLNITRONE
 ALPHA-(4-PYRIDYL 1-OXIDE)-N-TERT-BUTYLNITRONE
 ALPHA-(4-PYRIDYL N-OXIDE)-N-TERT-BUTYLNITRONE
 N-TERT-BUTYL-ALPHA-(4-PYRIDYL-1-OXIDE)NITRONE
 N-TERT-BUTYL-ALPHA-(4-PYRIDYL)-NITRONE N'-OXIDE
 alpha-(4-Pyridyl N-oxide)-N-tert-butylnitrone 99%
 alpha-(4-Pyridyl N-oxide)-N-tert-butylnitrone ~95%
 alpha-(4-Pyridyl 1-oxide)-N-tert-butyl-nitrone,99%
 N-(4-PYRIDYLMETHYLENE)-TERT-BUTYLAMINE N,N'-DIOXIDE
 alpha-(4-Pyridyl 1-oxide)-N-tert-butyl-nitrone, 99% 100MG
 1,1-dimethyl-N-(4-pyridylmethylene)ethylamine N,N'-dioxide
 N-[(Pyridine 1-oxide)-4-ylmethylene]-tert-butylamineN-oxide
 N-tert-Butyl-alpha-(4-pyridyl-1-oxide)nitrone [spin trapping
 2-Methyl-N-[(pyridine 1-oxide)-4-ylmethylene]-2-propanamine oxide
 (Z)-2-Methyl-N-((1-oxidopyridin-4-yl)methylene)propan-2-amine oxide
 N-[[(Pyridine-1-oxide)-4-yl]methylene]-1,1-dimethylethanamine-N-oxide
 N-TERT-BUTYL-ALPHA-(4-PYRIDYL-1-OXIDE)NITRONE [SPIN TRAPPING REAGENT]
 Dimethylaminoparthenolide/  Tert-Butyl-[(1-Oxido-4-Pyridylidene)Methyl]-Oxo-Ammonium
 POBN,  N-tert-Butyl-α-(4-pyridyl)nitrone  Nμ-oxide,  N-(4-Pyridylmethylene)-tert-butylamine  N,Nμ-dioxide
 α-(4-Pyridyl N-oxide)-N-tert-butylnitrone,N-(4-Pyridylmethylene)-tert-butylamine N,N′-dioxide, N-tert-Butyl-α-(4-pyridyl)nitrone N′-oxide, POBN
 N-tert-Butyl-alpha-(4-pyridyl)nitrone N'-Oxide
POBN
N-(4-Pyridylmethylene)-tert-butylamine N,N'-Dioxide
alpha-(4-Pyridyl N-Oxide)-N-tert-butylnitrone
 |  | [EINECS(EC#)] 
 266-512-3
 |  | [Molecular Formula] 
 C10H14N2O2
 |  | [MDL Number] 
 MFCD00041022
 |  | [MOL File] 
 66893-81-0.mol
 |  | [Molecular Weight] 
 194.23
 | 
 | Chemical Properties | Back Directory |  | [Appearance] 
 white to pale yellow crystalline powder
 |  | [Melting point ] 
 183-185 °C(lit.)
 
 |  | [Boiling point ] 
 330.68°C (rough estimate)
 |  | [density ] 
 1.1444 (rough estimate)
 |  | [refractive index ] 
 1.5000 (estimate)
 |  | [storage temp. ] 
 2-8°C
 
 |  | [solubility ] 
 water: soluble10mg/mL, clear, colorless to faintly yellow
 |  | [form ] 
 White to off-white or colorless crystalline solid.
 |  | [pka] 
 0.76±0.53(Predicted)
 |  | [color ] 
 White to Light yellow
 |  | [Water Solubility ] 
 water: soluble 10mg/mL, clear, colorless to faintly yellow
 |  | [BRN ] 
 1453764
 | 
 | Hazard Information | Back Directory |  | [Chemical Properties] 
 white to pale yellow crystalline powder
 |  | [Uses] 
 Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.
 |  | [in vivo] 
 
 Electron spin resonance (ESR) spectrum of radical adducts detected in bile of rats 1 h after acute Sodium formate (2 g/kg) and POBN (1.5 g/kg) i.p. administration[1]. | Animal Model: | Fischer male rats (300-400 g)[1] |  | Dosage: | 1.5 g/kg (Pharmacokinetic Analysis) |  | Administration: | Injected simultaneously i.p. |  | Result: | A strong six-line ESR signal of the POBN radical adduct was detected in the bile of rats after acute sodium formate poisoning. | 
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                            | Company Name: | Energy Chemical |  
                            | Tel: | 021-021-58432009 400-005-6266 |  
                            | Website: | http://www.energy-chemical.com |  |