| Identification | Back Directory | [Name]
Daniquidone | [CAS]
67199-66-0 | [Synonyms]
BAYH-2049
NSC-320846
batracylin
Daniquidone
Batracyclin
NSC 320846|||BAY-H 2049
8-Aminoisoindolo[1,2-b]quinazolin-12(10H)-one
Isoindolo[1,2-b]quinazolin-12(10H)-one, 8-amino- | [Molecular Formula]
C15H11N3O | [MDL Number]
MFCD00866448 | [MOL File]
67199-66-0.mol | [Molecular Weight]
249.27 |
| Hazard Information | Back Directory | [Uses]
Batracylin (NSC320846) is a potent DNA Topoisomerases I and DNA Topoisomerases II inhibitor. Batracylin shows cytotoxicity and antiproliferative activity. Batracylin induces DNA breaks[1]. | [References]
[1] Rao VA, et al. Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage. Cancer Res. 2007 Oct 15;67(20):9971-9. DOI:10.1158/0008-5472.CAN-07-0804 |
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