ChemicalBook--->CAS DataBase List--->67287-54-1

67287-54-1

67287-54-1 Structure

67287-54-1 Structure
IdentificationBack Directory
[Name]

6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide
[CAS]

67287-54-1
[Synonyms]

SKF 82526 HydrobroMide
FenoldopaM HydrobroMide
(±)-SKF 82526 HydrobroMide
FENOLDOPAM MONOHYDROBROMIDE
6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol HydrobroMide
6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide
6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1h-3-benzazepine-7,8-diol monohydrobromide
[EINECS(EC#)]

266-634-7
[Molecular Formula]

C16H16ClNO3.BrH
[MDL Number]

MFCD27977921
[MOL File]

67287-54-1.mol
[Molecular Weight]

386.67
Chemical PropertiesBack Directory
[Melting point ]

>233°C (dec.)
[storage temp. ]

2-8°C
[solubility ]

DMSO: >12mg/mL
[form ]

Solid
[color ]

off-white
Hazard InformationBack Directory
[Uses]

Dopamine D1-receptor agonist. Antihypertensive.
[Biochem/physiol Actions]

Fenoldopam is a selective dopamine agonist that is being considered for the parenteral treatment of systemic hypertension. In both an oral and parenteral form, fenoldopam causes peripheral vasodilation by stimulating dopamine-1 adrenergic receptors. Intravenous fenoldopam may provide advantages over sodium nitroprusside because it can induce both a diuresis and natriuresis, is not light sensitive, and is not associated with cyanide toxicity. There is no evidence for rebound hypertension after discontinuation of fenoldopam infusion.
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H317-H319-H334
[Precautionary statements ]

P261-P280-P305+P351+P338-P342+P311
[Hazard Codes ]

Xn
[Risk Statements ]

22-36-42/43
[Safety Statements ]

22-26-36/37/39
[WGK Germany ]

3
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