Identification | Back Directory | [Name]
Eupatolide | [CAS]
6750-25-0 | [Synonyms]
Eupatolide (3aR,4R,6E,10E,11aR)-3a,4,5,8,9,11a-Hexahydro-4-hydroxy-6,10-dimethyl-3-methylenecyclodeca[b]furan-2(3H)-one Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-4-hydroxy-6,10-dimethyl-3-methylene-, (3aR,4R,6E,10E,11aR)- | [Molecular Formula]
C15H20O3 | [MDL Number]
MFCD31746806 | [MOL File]
6750-25-0.mol | [Molecular Weight]
248.32 |
Chemical Properties | Back Directory | [Melting point ]
182.1-188.1 °C | [Boiling point ]
438.7±45.0 °C(Predicted) | [density ]
1.11±0.1 g/cm3(Predicted) | [pka]
13.92±0.60(Predicted) | [LogP]
2.820 (est) |
Hazard Information | Back Directory | [Uses]
Eupatolide is an antitumor agent that can be isolated from Eupatorium formosanum. Eupatolide has cytotoxic activity and inhibits human epidermoid carcinoma of larynx cell growth in vitro[1]. | [Definition]
ChEBI: Eupatolide is a germacranolide with formula C15H20O3, isolated from several Inula species. It exhibits anti-cancer properties. It has a role as an antineoplastic agent and a plant metabolite. It is a germacranolide, a homoallylic alcohol, a secondary alcohol and a gamma-lactone. | [References]
[1] Lee KH, et al. Eupatolide, a new cytotoxic principle from Eupatorium formosanum HAY. J Pharm Sci. 1972 Apr;61(4):629-31. DOI:10.1002/jps.2600610432 |
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