| Identification | Back Directory | [Name]
4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]- | [CAS]
676266-31-2 | [Synonyms]
Sudoterb
Sudoterb (LL3858)
Sudoterb free base
4-PyridinecarboxaMide, N-[2-Methyl-5-phenyl-3-[[4-[3-(trifluoroMethyl)phenyl]-1-piperazinyl]Methyl]-1H-pyrrol-1-yl]- | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C29H28F3N5O | [MDL Number]
MFCD19443167 | [MOL File]
676266-31-2.mol | [Molecular Weight]
519.56 |
| Hazard Information | Back Directory | [Uses]
Sudoterb (LL 3858) is an orally active anti-Tuberculosis agent[1]. | [in vivo]
Sudoterb (12.5 mg/kg and 25 mg/kg, p.o., 4 and 8 weeks) is effective against M.tuberculosis in mice[2].
Sudoterb (p.o., mice) shows a LD50 of 700 mg/kg[2].
| [References]
[1] Maha A. Elhakeem, et al. Synthesis and anti-mycobacterial evaluation of some new isonicotinylhydrazide analogues. Bulletin of Faculty of Pharmacy, Cairo University. 2015, 53 (1), 45-52
[2] Protopopova M, et al. In search of new cures for tuberculosis. Med Chem. 2007 May;3(3):301-16. DOI:10.2174/157340607780620626 |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
| Company Name: |
cjbscvictory
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| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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