Identification | Back Directory | [Name]
GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU | [CAS]
67810-56-4 | [Synonyms]
β-lipotropin 62-77 des-tyr1-γ-endorphin BETA-ENDORPHIN (2-17) [Des-Tyr1] g-Endorphin BETA-LIPOTROPIN (62-77) DES-TYR1-GAMMA-ENDORPHIN des-tyr(1)-gamma-endorphi gamma-endorphin, des-Tyr(1)- 2-16-α-Endorphin (sheep), 16a-L-leucine- GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU H-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU-OH GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU: GGFMTSEKSQTPLVTL | [Molecular Formula]
C74H122N18O25S | [MDL Number]
MFCD00076397 | [MOL File]
67810-56-4.mol | [Molecular Weight]
1695.93 |
Hazard Information | Back Directory | [Uses]
[Des-Tyr1]-gamma-Endorphin is a neuropeptide, which can be found in human cerebrospinal fluid. [Des-Tyr1]-gamma-Endorphin exhibits antidepressant efficacy, facilitates the extinction of active avoidance and attenuates the passive avoidance behavior in rats[1]. | [References]
[1] Manchanda R, et al., (Des‐tyr1)‐gamma‐endorphin (DTγE) in the treatment of depression: Double‐blind placebo‐controlled trial[J]. Human Psychopharmacology: Clinical and Experimental, 1986, 1(2): 99-102. |
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