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67810-56-4

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67810-56-4 Structure

67810-56-4 Structure
IdentificationBack Directory
[Name]

GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU
[CAS]

67810-56-4
[Synonyms]

β-lipotropin 62-77
des-tyr1-γ-endorphin
BETA-ENDORPHIN (2-17)
[Des-Tyr1] g-Endorphin
BETA-LIPOTROPIN (62-77)
DES-TYR1-GAMMA-ENDORPHIN
des-tyr(1)-gamma-endorphi
gamma-endorphin, des-Tyr(1)-
2-16-α-Endorphin (sheep), 16a-L-leucine-
GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU
H-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU-OH
GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU: GGFMTSEKSQTPLVTL
[Molecular Formula]

C74H122N18O25S
[MDL Number]

MFCD00076397
[MOL File]

67810-56-4.mol
[Molecular Weight]

1695.93
Chemical PropertiesBack Directory
[RTECS ]

JZ2250000
[storage temp. ]

−20°C
[form ]

Solid
[Sequence]

Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

[Des-Tyr1]-gamma-Endorphin is a neuropeptide, which can be found in human cerebrospinal fluid. [Des-Tyr1]-gamma-Endorphin exhibits antidepressant efficacy, facilitates the extinction of active avoidance and attenuates the passive avoidance behavior in rats[1].
[References]

[1] Manchanda R, et al., (Des‐tyr1)‐gamma‐endorphin (DTγE) in the treatment of depression: Double‐blind placebo‐controlled trial[J]. Human Psychopharmacology: Clinical and Experimental, 1986, 1(2): 99-102.
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