ChemicalBook--->CAS DataBase List--->68192-15-4

68192-15-4

68192-15-4 Structure

68192-15-4 Structure
IdentificationBack Directory
[Name]

N,N-DIMETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE
[CAS]

68192-15-4
[Synonyms]

Prostaglandin F2α dimethyl amide
Prostaglandin F2α dimethyl amide
PROSTAGLANDIN F2ALPHA DIMETHYL AMIDE
N,N-DIMETHYL-9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE
Prosta-5,13-dien-1-amide, 9,11,15-trihydroxy-N,N-dimethyl-, (5Z,9α,11α,13E,15R)- (9CI)
[Molecular Formula]

C22H39NO4
[MDL Number]

MFCD00797652
[MOL File]

68192-15-4.mol
[Molecular Weight]

381.55
Chemical PropertiesBack Directory
[solubility ]

DMF: >50 mg/ml (from PGF2a dimethyl; DMSO: >50 mg/ml (from PGF2a dimethyl; Ethanol: >20 mg/ml (from PGF2a dimethyl; Methyl Acetate: >10 mg/ml (from PGF2a dimethyl; PBS pH 7.2: >3 mg/ml (from PGF2a dimethyl
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H360-H336
[Precautionary statements ]

P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

Prostaglandin F (PGF) dimethyl amide is a weak FP receptor antagonist.1 In gerbil colon, PGF dimethyl amide at a dose of 3.2 μg/ml inhibits the contractile effects of PGF (at 6 ng/ml) by 50%.1
[Uses]

Prostaglandin F2α dimethyl amide is an antagonist for Prostaglandin F2α (HY-12956), which blocks 50% contraction on gerbilMeriones unguiculatus colon induced by PGF2α at 3.2 μg/mL[1].
[References]

1. Maddox, Y.T., Ramwell, P.T., Shiner, C.S., et al. Amide and l-amino derivatives of F prostaglandins as prostaglandin antagonists Nature 273,549-552(1978).
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