ChemicalBook--->CAS DataBase List--->682793-07-3

682793-07-3

682793-07-3 Structure

682793-07-3 Structure
IdentificationBack Directory
[Name]

AP-C2
[CAS]

682793-07-3
[Synonyms]

[Molecular Formula]

C18H16N4S
[MOL File]

682793-07-3.mol
[Molecular Weight]

320.41
Chemical PropertiesBack Directory
[Boiling point ]

594.6±60.0 °C(Predicted)
[density ]

1.336±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka]

17.17±0.30(Predicted)
Hazard InformationBack Directory
[Uses]

AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2[1].
[References]

[1] Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181. DOI:10.1074/jbc.RA118.002835
Spectrum DetailBack Directory
[Spectrum Detail]

AP-C2(682793-07-3)1HNMR
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