| Identification | Back Directory | [Name]
ANTI-CDC27 | [CAS]
682795-78-4 | [Synonyms]
APC3 CDC27 H-NUC ANAPC3 CDC27Hs D0S1430E Anti-HNUC Anti-APC3 ANTI-CDC27 Anti-D0S1430E Anti-D17S978E MONOCLONAL ANTI-CDC27 Anti-Cell division cycle 27 Anti-Anaphase promoting complex 3 Anti-APC3 antibody produced in rabbit Anti-CDC27 antibody produced in rabbit Anti-H-NUC antibody produced in rabbit Cell division cycle protein 27 homolog Anti-cell division cycle 27 homolog (S. cerevisiae) Monoclonal Anti-Cdc27 antibody produced in mouse 2-Pyrimidinamine, 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]- | [Molecular Formula]
C22H23N3O4 | [MDL Number]
MFCD01633250 | [MOL File]
682795-78-4.mol | [Molecular Weight]
393.44 |
| Chemical Properties | Back Directory | [Boiling point ]
596.455±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.250±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
−20°C | [form ]
buffered aqueous solution | [pka]
3.777±0.10(predicted) | [biological source]
rabbit |
| Hazard Information | Back Directory | [Uses]
AP-C3 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.3. AP-C3 only weakly inhibits cGKII-dependent anion secretion[1]. | [References]
[1] Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181. DOI:10.1074/jbc.RA118.002835 |
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Atlas antibodies
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Merck KGaA
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