| Identification | Back Directory | [Name]
2-HYDROXY-5-IODO-BENZONITRILE | [CAS]
685103-95-1 | [Synonyms]
5-IODO-2-HYDROXYBENZONITRILE
2-HYDROXY-5-IODO-BENZONITRILE
2-HYDROXY-5-IODO-BENZONITRILE ISO 9001：2015 REACH | [Molecular Formula]
C7H4INO | [MDL Number]
MFCD02683857 | [MOL File]
685103-95-1.mol | [Molecular Weight]
245.02 |
| Chemical Properties | Back Directory | [Melting point ]
115-117℃ | [Boiling point ]
321℃ | [density ]
2.09 | [Fp ]
148℃ | [storage temp. ]
2-8°C, protect from light, stored under nitrogen | [pka]
6.55±0.18(Predicted) | [Appearance]
White to light yellow Solid |
| Questions And Answer | Back Directory | [Application]
2-Hydroxy-5-iodobenzonitrile is an organic intermediate that can be used to prepare tert-butyl 4-((2-(aminomethyl)-4-iodophenoxy)methyl)piperidine-1-carboxylate. 4-((2-(aminomethyl)-4-iodophenoxy)methyl)piperidine-1-carboxylate and related derivatives have wide applications in medicinal chemistry and organic synthesis. |
| Hazard Information | Back Directory | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 70, p. 8590, 2005 DOI: 10.1021/jo051191x | [Synthesis]
(1)Synthesis of 5-iodo-2-hydroxybenzaldehyde oxime Add 30g 5-iodo-2-hydroxybenzaldehyde to 270ml ethanol, dropwise add 17g hydroxylamine hydrochloride, room temperature stirring overnight, cooling, add water and ethyl acetate, extraction and part |
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