| Identification | Back Directory | [Name]
(5R)-5-hydroxy-7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-3-heptanone | [CAS]
68622-73-1 | [Synonyms]
(R)-5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylheptan-3-one
(5R)-5-hydroxy-7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-3-heptanone | [Molecular Formula]
C20H24O4 | [MOL File]
68622-73-1.mol | [Molecular Weight]
328.402 |
| Hazard Information | Back Directory | [Uses]
Antiviral agent 41 (compound 5) is a diarylheptanoid isolated from Alpinia officinarum. Antiviral agent 41 exhibits potential antiviral activity against influenza virus in vitro[1]. | [Definition]
ChEBI: (5R)-5-hydroxy-7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-3-heptanone is a beta-hydroxy ketone that is (5R)-5-hydroxyheptan-3-one substituted by a phenyl group at position 1 and a 4-hydroxy-3-methoxyphenyl moiety at position 7. Isolated from Alpinia officinarum, it exhibits antiviral activity against influenza virus. It has a role as an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor and a plant metabolite. It is a beta-hydroxy ketone and a member of guaiacols. | [References]
[1] Sawamura R, et al. Antiviral activities of diarylheptanoids against influenza virus in vitro. J Nat Med. 2010 Jan;64(1):117-20. DOI:10.1007/s11418-009-0372-2 |
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