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69123-97-3

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69123-97-3 Structure

69123-97-3 Structure
IdentificationBack Directory
[Name]

2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
[CAS]

69123-97-3
[Synonyms]

5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine
5-Bromo-2’-deoxy-2’-fluoro-b-D-arabinouridine
5-BroMo-2'-deoxy-2'-fluoro-beta-D-arabinouridine
1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-bromouracil
2,4(1H,3H)-PyriMidinedione, 5-broMo-1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-
2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
5-Bromo-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione
2,4(1H,3H)-PyriMidinedione, 5-broMo-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-
[Molecular Formula]

C9H10BrFN2O5
[MOL File]

69123-97-3.mol
[Molecular Weight]

325.089
Chemical PropertiesBack Directory
[density ]

1.98±0.1 g/cm3(Predicted)
[pka]

7.73±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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