691868-19-6

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691868-19-6 Structure

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[Name] Iso-Fludelone
[CAS] 691868-19-6
[Synonyms] Iso-Fludelone (4S,7R,8S,9S,10E,13E,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-(5-methyl-1,2-oxazol-3-yl)prop-1-en-2-yl]-13-(trifluoromethyl)-1-oxacyclohexadeca-10,13-diene-2,6-dione Oxacyclohexadeca-10,13-diene-2,6-dione, 4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(1E)-1-methyl-2-(5-methyl-3-isoxazolyl)ethenyl]-13-(trifluoromethyl)-, (4S,7R,8S,9S,10E,13E,16S)-
[Molecular Formula] C27H36F3NO6
[MOL File] 691868-19-6.mol
[Molecular Weight] 527.57

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[Uses] Isofludelone (KOS-1803) is a potential microtubule stabilizer for the treatment of solid tumors. Isofludelone has antitumor activity[1].
[References] [1] Christner SM, et al. Quantitative method for the determination of iso-fludelone (KOS-1803) in human plasma by LC-MS/MS. J Pharm Biomed Anal. 2014 Nov;100:199-204. DOI:10.1016/j.jpba.2014.08.007

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