ChemicalBook--->CAS DataBase List--->6937-28-6

6937-28-6

6937-28-6 Structure

6937-28-6 Structure
IdentificationBack Directory
[Name]

ethylalpha-bromodiethylacetate
[CAS]

6937-28-6
[Synonyms]

NSC 41719
α-BromodiethyL
Ethyl 2-BroMo-2-ethylbutyrate
α-Bromodiethylacetic Acid Ethyl Ester
α-BroModiethylacetic Acid Ethyl Ester
2-BroMo-2-ethylbutyric Acid Ethyl Ester
Butanoic acid, 2-bromo-2-ethyl-, ethyl ester
[Molecular Formula]

C8H15BrO2
[MOL File]

6937-28-6.mol
[Molecular Weight]

223.11
Chemical PropertiesBack Directory
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
Hazard InformationBack Directory
[Uses]

ethylalpha-bromodiethylacetate is an α-bromo tertiary ester used as a reagent in in organic synthesis.
[Application]

Ethyl 2-bromo-2-ethylbutanoate can be used as an alkylating agent in rhodium-catalyzed C2-branched alkylation of benzimidazole.
[References]

[1] Johansson*, L., Fotsch, C., Bartberger, M. D., Castro, V. M., Chen, M., Emery, M., Gustafsson, S., Hale, C., Hickman, D., Homan, E., Jordan, S. R., Komorowski, R., Li, A., McRae, K., Moniz, G., Matsumoto, G., Orihuela, C., Palm, G., Veniant, M., … Zhang, J. (2008). 2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors: Enzyme−Ligand Co-Crystal Structure and Demonstration of Pharmacodynamic Effects in C57Bl/6 Mice. Journal of Medicinal Chemistry, 51 10, 2933–2943. https://doi.org/10.1021/jm701551j
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