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69504-14-9

69504-14-9 Structure

69504-14-9 Structure
IdentificationBack Directory
[Name]

3'-O-tert-Butyldimethylsilyladenosine
[CAS]

69504-14-9
[Synonyms]

3'-O-TBDMS adenosine
3'-O-TBDMS-adenosine
3'-O-t-ButyldiMethylsilyl adenosine
3’-O-t-Butyldimethylsilyl adenosine
3'-O-tert-Butyldimethylsilyladenosine
3'-O-Tert-Butyldimethylsilyladenosine
Adenosine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI)
[Molecular Formula]

C16H27N5O4Si
[MDL Number]

MFCD20134041
[MOL File]

69504-14-9.mol
[Molecular Weight]

381.5
Chemical PropertiesBack Directory
[Boiling point ]

572.2±60.0 °C(Predicted)
[density ]

1.39±0.1 g/cm3(Predicted)
[pka]

12.98±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

3’-O-t-Butyldimethylsilyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
[References]

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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