| Identification | Back Directory | [Name]
N-METHYL-1-DEOXYNOJIRIMYCIN | [CAS]
69567-10-8 | [Synonyms]
Mednj
MOR-14
N-MDJN
Aids000354
Aids-000354
N-Methylmoranolin
N-METHYLDEOXYNOJIRIMYCIN
DEOXYNOJIRIMYCIN, N-METHYL-
N-METHYL-1-DEOXYNOJIRIMYCIN
1,5-DIDEOXY-1,5-IMINO-1-METHYL-D-SORBITOL
N-METHYL-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL
(2R)-1-Methyl-2α-(hydroxymethyl)-3β,4α,5β-piperidinetriol
(2R)-2α-(Hydroxymethyl)-1-methyl-3β,4α,5β-piperidinetriol
(2R,3R,4R,5S)-2-(HydroxyMethyl)-1-Methyl-3,4,5-piperidinetriol
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-methylpiperidine-3,4,5-triol
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-1-methyl-, (2R,3R,4R,5S)-
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-1-methyl-, [2R-(2A,3B,4A,5B)]- | [EINECS(EC#)]
203-703-2 | [Molecular Formula]
C7H15NO4 | [MDL Number]
MFCD00133609 | [MOL File]
69567-10-8.mol | [Molecular Weight]
177.2 |
| Chemical Properties | Back Directory | [Appearance]
White to Off-White | [Melting point ]
126-128°C | [Boiling point ]
367.2±42.0 °C(Predicted) | [density ]
1.394±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
Methanol (Slightly, Sonicated), Water (Slightly) | [form ]
Solid | [pka]
13.71±0.70(Predicted) | [color ]
White to Off-White | [biological source]
synthetic (organic) | [BRN ]
1524564 | [Stability:]
Hygroscopic | [InChI]
1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1 | [InChIKey]
AAKDPDFZMNYDLR-XZBKPIIZSA-N | [SMILES]
CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White | [Uses]
Interfers with the normal processing of N-linked glycoproteins by inhibiting the action of glucosidases that remove glycosyl residues from Glc3Man9GlcNAc2 following the addition of this moiety to a nascent polypeptide | [General Description]
Chemical structure: glucosamine | [Biochem/physiol Actions]
Interferes with metabolism of N-linked glycoproteins by inhibition of glucosidase. | [in vivo]
N-Methylmoranoline decreases the alpha-1,6-glucosidase activity to approximately 20%, reduces the glycogen breakdown, and attenuates the lactate accumulation at both 10 and 30 minutes of ischemia[1]. MOR-14 is protective against postischemic left ventricular dysfunction through the inhibition of glycogenolysis in the isolated rat heart[3]. |
|
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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