| Identification | Back Directory | [Name]
2-Pyridinamine, 5-chloro-N-[4-(2-pyridinyl)-2-thiazolyl]- | [CAS]
696628-24-7 | [Synonyms]
2-Pyridinamine, 5-chloro-N-[4-(2-pyridinyl)-2-thiazolyl]- | [Molecular Formula]
C13H9ClN4S | [MOL File]
696628-24-7.mol | [Molecular Weight]
288.76 |
| Chemical Properties | Back Directory | [Boiling point ]
478.5±55.0 °C(Predicted) | [density ]
1.430±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
1.60±0.10(Predicted) | [color ]
Light brown to brown |
| Hazard Information | Back Directory | [Uses]
BAY 249716 stabilizes all three p53 protein variants. BAY 249716 also has antitubercular activity (IC90: <0.10 μg/mL for Tuberculosis)[1][2]. | [References]
[1] Lemos C, et al. Identification of Small Molecules that Modulate Mutant p53 Condensation. iScience. 2020 Sep 1;23(9):101517. DOI:10.1016/j.isci.2020.101517
[2] Ananthan S, et al. High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv. Tuberculosis (Edinb). 2009 Sep;89(5):334-53. DOI:10.1016/j.tube.2009.05.008 |
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