| Identification | Back Directory | [Name]
3',5'-DIACETYLTHYMIDINE | [CAS]
6979-97-1 | [Synonyms]
DIACETYL THYMIDINE
3',5'-DIACETYLTHYMIDINE
Thymidine, 3',5'-diacetate
3'-O,5'-O-Diacetylthymidine
3',5'-DI-O-ACETYL-THYMIDINE
3',5'-DIACETYLTHYMIDINE, 99+%
1'(2'-DEOXY-3',5'-DI-O-ACETYL-BETA-D-RIBOFURANOSYL)THYMINE
1-(3-O,5-O-Diacetyl-2-deoxy-β-D-ribofuranosyl)-5-methyl-1,2,3,4-tetr
1-(3-O,5-O-Diacetyl-2-deoxy-β-D-ribofuranosyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione | [EINECS(EC#)]
230-244-5 | [Molecular Formula]
C14H18N2O7 | [MDL Number]
MFCD00010630 | [MOL File]
6979-97-1.mol | [Molecular Weight]
326.3 |
| Chemical Properties | Back Directory | [Appearance]
white crystals or crystalline powder | [Melting point ]
126-128 °C(lit.) | [Boiling point ]
463.51°C (rough estimate) | [density ]
1.2368 (rough estimate) | [refractive index ]
1.5080 (estimate) | [storage temp. ]
0-6°C | [pka]
9.55±0.10(Predicted) | [CAS DataBase Reference]
6979-97-1 |
| Hazard Information | Back Directory | [Chemical Properties]
white crystals or crystalline powder | [Uses]
3’,5’-Di-O-acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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