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70169-39-0

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70169-39-0 Structure

70169-39-0 Structure
IdentificationBack Directory
[Name]

Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide
[CAS]

70169-39-0
[Synonyms]

WAY-358024
2-hydroxy-N'-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)benzohydrazide
Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide
[Molecular Formula]

C15H11N3O3
[MOL File]

70169-39-0.mol
[Molecular Weight]

281.27
Chemical PropertiesBack Directory
[Melting point ]

>250 °C
[density ]

1.44±0.1 g/cm3(Predicted)
[pka]

8.26±0.30(Predicted)
Hazard InformationBack Directory
[Uses]

GSK-3β inhibitor 26 (Compound D14) is a GSK-3β inhibitor with an IC50 of 18.23 μM. GSK-3β inhibitor 26 can be used in the research of cancer, inflammation and neurodegenerative diseases[1].
[IC 50]

GSK-3β: 18.23 μM (IC50)
[References]

[1] Dou X, et al. Discovery of new GSK-3β inhibitors through structure-based virtual screening. Bioorg Med Chem Lett. 2018 Jan 15;28(2):160-166. DOI:10.1016/j.bmcl.2017.11.036
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