| Identification | Back Directory | [Name]
N,N-dimethyldoxorubicin | [CAS]
70222-95-6 | [Synonyms]
N,N-dimethyldoxorubicin
5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)- | [Molecular Formula]
C29H33NO11 | [Molecular Weight]
571.57 |
| Hazard Information | Back Directory | [Uses]
N,N-Dimethyldoxorubicin is a Doxorubicin (HY-15142A) analogue. N,N-Dimethyldoxorubicin shows cytotoxicity against a panel of tumor cell lines (IC50s < 0.3 μM)[1]. | [References]
[1] Wander DPA, et al. Synthetic (N,N-Dimethyl)doxorubicin Glycosyl Diastereomers to Dissect Modes of Action of Anthracycline Anticancer Drugs. J Org Chem. 2021 Apr 16;86(8):5757-5770. DOI:10.1021/acs.joc.1c00220 |
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