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702679-55-8

702679-55-8 Structure

702679-55-8 Structure
IdentificationBack Directory
[Name]

Boc-trans-Pro(4-azido)-OH·DCHA
[CAS]

702679-55-8
[Synonyms]

Fmoc-(4R)-azido-L-Proline
Fmoc-(2S,4R)-4-azidoproline
Fmoc-L-Pro(4R-N3)-OH (2S,4R)
trans-4-Azido-N-Fmoc-L-proline
Boc-trans-Pro(4-azido)-OH·DCHA
Fmoc-(4R)-azido-L-Proline≥ 99% (HPLC)
(2S,4R)-Fmoc-4-azido-pyrrolidine-2-carboxylic acid
(2S,4R)-Boc- 4-azido-pyrrolidine-2-carboxylic acid·DCHA
(2S,4R)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-azidopyrrolidine-2-carboxylic acid
[Molecular Formula]

C20H18N4O4
[MDL Number]

MFCD21363169
[MOL File]

702679-55-8.mol
[Molecular Weight]

378.381
Chemical PropertiesBack Directory
[Melting point ]

55-58 °C
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS08
[Signal word ]

Warning
[Hazard statements ]

H373
[Precautionary statements ]

P260-P314-P501
[HS Code ]

2929900090
Hazard InformationBack Directory
[Chemical Properties]

White crystalline powder
[Uses]

(2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide[1]. (2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
[References]

[1] Lewandowska U, et al. Hierarchical supramolecular assembly of sterically demanding π-systems by conjugation with oligoprolines. Angew Chem Int Ed Engl. 2014 Nov 10;53(46):12537-41. doi: 10.1002/anie.201408279. Epub 2014 Oct 10. DOI:10.1002/anie.201408279
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