| Identification | Back Directory | [Name]
Tolnapersine | [CAS]
70312-00-4 | [Synonyms]
BK 34-530
TOLNAPERSINE
Tolnapersine ISO 9001：2015 REACH
6-[4-(2-Methylphenyl)-1-piperazinyl]-5,6,7,8-tetrahydro-2-naphthol
6-(4-(2-Methylphenyl)-1-piperazinyl)-5,6,7,8-tetrahydronaphthalen-2-ol
2-Naphthalenol, 5,6,7,8-tetrahydro-6-[4-(2-methylphenyl)-1-piperazinyl]- | [Molecular Formula]
C21H26N2O | [MDL Number]
MFCD00868812 | [MOL File]
70312-00-4.mol | [Molecular Weight]
322.44 |
| Hazard Information | Back Directory | [Uses]
Tolnapersine exhibits multidrug resistance (MDR) reversal activity, which reverses the resistance of tumor cells to multiple chemotherapy drugs by affecting P-glycoprotein (Pgp) on the cell membrane[1]. | [References]
[1] Ramu A, et al., Reversal of multidrug resistance by bis(phenylalkyl)amines and structurally related compounds. Cancer Chemother Pharmacol. 1994;34(5):423-30. DOI:10.1007/BF00685568 |
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