| Identification | Back Directory | [Name]
aflatrem | [CAS]
70553-75-2 | [Synonyms]
aflatrem
9-(1,1-Dimethyl-2-propenyl)-2,3,5b,6,7,7aα,8,13,13b,13c,14,15-dodecahydro-5bβ-hydroxy-2,2,13bβ,13cα-tetramethyl-4H-3β,15aβ-epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one
4H-3,15a-Epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one, 9-(1,1-dimethyl-2-propen-1-yl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R,5bS,7aS,13bS,13cR,15aS)- | [Molecular Formula]
C32H39NO4 | [MOL File]
70553-75-2.mol | [Molecular Weight]
501.66 |
| Chemical Properties | Back Directory | [Occurrence]
An alkaloidal metabolite of Aspergillus flavus, this tremorgenic toxin is established from chemical degradations and spectroscopic data. |
| Hazard Information | Back Directory | [Uses]
Aflatrem is a mycotoxin that can be isolated from Aspergillus flavus. Aflatrem has acute neurotoxic effects and can be ued in neurological disease[1]. | [Definition]
ChEBI: Aflatrem is an organooxygen compound and an organic heterotricyclic compound. | [References]
[1] Valdes JJ, et al. Aflatrem: a tremorgenic mycotoxin with acute neurotoxic effects. Environ Health Perspect. 1985 Oct;62:459-63. DOI:10.1289/ehp.8562459 |
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