| Identification | Back Directory | [Name]
2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE | [CAS]
7057-48-9 | [Synonyms]
D4A
NSC 108602
BETA-L-D4A
Compound FL0097
Didanosin EP Imp I
Didanosine EP Impurity I
2',3'-Dideoxy-2'3'-didehy...
2'3'-didehydro-2'3'-dideoxyadenosine
2',3'-Dideoxy-2',3'-didehydroadenosine
Adenosine, 2',3'-didehydro-2',3'-dideoxy-
Didanosine Impurity 9（Didanosine EP Impurity I）
9-(2,3-Dideoxy-β-D-glycero-2-pentenofuranosyl)-9H-purine-6-amine
9-(2,3-Dideoxy-β-D-glycero-penta-2-enofuranosyl)-9H-purin-6-amine
[(2S,5R)-5-(6-amino-9H-purin-9-yl)-2,5-dihydrofuran-2-yl]methanol
9-(2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)-9H-purin-6-amine (2′,3′-dideoxy-2′,3′-didehydroadenosine) | [Molecular Formula]
C10H11N5O2 | [MDL Number]
MFCD00040965 | [MOL File]
7057-48-9.mol | [Molecular Weight]
233.23 |
| Chemical Properties | Back Directory | [Melting point ]
187-189°C | [Boiling point ]
553.9±60.0 °C(Predicted) | [density ]
1.74±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C(protect from light) | [solubility ]
Soluble in DMSO | [pka]
14.28±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
2’,3’-Dideoxy-2,3-didehydroadenosine (Didanosine EP Impurity I) is an impurity of Didanosine (D440950), which is a purine analog (1) which used as an antiviral agent. Classed as an anti-retroviral drug used in the treatment of HIV in ART therapy, it also may increase acetaminophen related hepatotoxicity by enhancing mitochrondrial dysfunction (2). | [IC 50]
HIV-1 |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
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