| Identification | Back Directory | [Name]
Napirimus | [CAS]
70696-66-1 | [Synonyms]
Napirimus
Napirimus [inn]
Unii-45081sg6xt
1H-Pyrrole-2-carboxylic acid, 1-methyl-4-(1-naphthalenylcarbonyl)- | [Molecular Formula]
C17H13NO3 | [MDL Number]
MFCD00867590 | [MOL File]
70696-66-1.mol | [Molecular Weight]
279.29 |
| Chemical Properties | Back Directory | [Boiling point ]
536.6±35.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [solubility ]
DMSO: Slightly soluble: 0.1-1 mg/ml | [pka]
3.83±0.41(Predicted) |
| Hazard Information | Back Directory | [Description]
Napirimus is an immunosuppressant.1 It is efficacious and preventative in a rat model of polyarthritis induced by complete Freund’s adjuvant when administered at doses of 200 and 100 mg/kg, respectively. Napirimus is 50 and 90% protective against experimental autoimmune encephalomyelitis (EAE), previously known as allergic encephalomyelitis, in rats when administered at doses of 100 and 400 mg/kg, respectively.WARNING This product is not for human or veterinary use. | [References]
[1] Peptides having immunostimulating properties and pharmaceutical compositions containing them[J]. Vaccine, 1983, 1 1: Page 52. DOI: 10.1016/0264-410x(83)90037-3 |
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