| Identification | Back Directory | [Name]
chinifur | [CAS]
70762-66-2 | [Synonyms]
chinifur
N-[4-(diethylamino)-1-methylbutyl]-2-[(E)-2-(5-nitrofuran-2-...
2-[2-(5-Nitropyryl-2)ethenyl]-4-synolin carbonoic acid-1-diethylamino-4-pentylamide
N-(5-(Diethylamino)pentan-2-yl)-2-(2-(5-nitrofuran-2-yl)vinyl)quinoline-4-carboxamide
N-[1-Methyl-4-(diethylamino)butyl]-2-[2-(5-nitro-2-furanyl)ethenyl]quinoline-4-carboxamide
N-[1-Methyl-4-(diethylamino)butyl]-2-[2-(5-nitrofuran-2-yl)ethenyl]quinoline-4-carboxamide
N-[5-(diethylamino)pentan-2-yl]-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinoline-4-carboxamide
4-Quinolinecarboxamide,N-[4-(diethylamino)-1-methylbutyl]-2-[2-(5-nitro-2-furanyl)ethenyl]- | [Molecular Formula]
C25H30N4O4 | [MOL File]
70762-66-2.mol | [Molecular Weight]
450.53 |
| Chemical Properties | Back Directory | [Boiling point ]
621.7±55.0 °C(Predicted) | [density ]
1.202±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 5 mg/mL (11.10 mM);Ethanol: 2 mg/mL (4.44 mM) | [pka]
13.21±0.46(Predicted) | [Water Solubility ]
Water: Insoluble | [InChIKey]
MTHCJDYSIZMKAC-UHFFFAOYSA-N | [SMILES]
N1C2C(=CC=CC=2)C(C(NC(C)CCCN(CC)CC)=O)=CC=1C=CC1=CC=C([N+]([O-])=O)O1 |
| Hazard Information | Back Directory | [Uses]
Chinifur (Quinifuryl), a Nitrofuran derivative, is a selective inhibitor of trypanothione reductase and also a radical-generating substrate for trypanothione reductase (Ki = 4.5 μM)[1][2]. | [References]
[1] Iribarne F, et al. Interaction energies of nitrofurans with trypanothione reductase and glutathione reductase studied by molecular docking[J]. Journal of Molecular Structure: THEOCHEM, 2007, 818(1-3): 7-22.
[2] Cenas N, et al. Chinifur, a selective inhibitor and" subversive substrate" for Trypanosoma congolense trypanothione reductase[J]. Biochemical and biophysical research communications, 1994, 204(1): 224-229. DOI:10.1006/bbrc.1994.2448 |
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| Company Name: |
chemmole
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400-168-9330 15013243073 |
| Website: |
http://www.chemmolemall.com/ |
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