| Identification | Back Directory | [Name]
(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER | [CAS]
7101-51-1 | [Synonyms]
DOPA-METHYLESTER
L-DOPA Methyl Ester
levodopa methyl ester
Methyl 3-hydroxy-L-tyrosinate
3-Hydroxy-L-Tyrosine methyl ester
L-Tyrosine, 3-hydroxy-, Methyl ester
(S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate
methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER
(S)-2-AMino-3-(3,4-dihydroxy-phenyl)-propionic acid Methyl ester hydrochloride
MelevodopaQ: What is
Melevodopa Q: What is the CAS Number of
Melevodopa Q: What is the storage condition of
Melevodopa | [Molecular Formula]
C10H13NO4 | [MDL Number]
MFCD00870911 | [MOL File]
7101-51-1.mol | [Molecular Weight]
211.21 |
| Chemical Properties | Back Directory | [Boiling point ]
350.89°C (rough estimate) | [density ]
1.2545 (rough estimate) | [refractive index ]
1.5150 (estimate) | [storage temp. ]
2-8°C | [form ]
solid | [color ]
White |
| Hazard Information | Back Directory | [Description]
CHF-1301 was launched as an injection in Italy for the treatment of
patients with Parkinson's disease, particularly those with complications in their
clinical responses. CHF-1301 is the methyl ester of L-Dopa (levodopa), the
immediate precursor of dopamine. Thus, this prodrug is more soluble in water at
physiological pH, better absorbed and slowly transformed into levodopa in vivo;
it consequently improves the duration of action and prevents the rapid
fluctuations in response or involontary movements (dyskinesia) observed during chronic treatment with levodopa. In patients with a delayed effect of levodopa
(on-phenomenon) or a severe resistance to L-Dopa (off-phenomenon), CHF-
1301 significantly improves the onset and the stability of the'response. | [Originator]
Chiesi Farmaceutici SpA (Italy) | [Definition]
ChEBI: Melevodopa is a tyrosine derivative. | [Brand name]
Levomet |
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