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7101-51-1

7101-51-1 Structure

7101-51-1 Structure
IdentificationBack Directory
[Name]

(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER
[CAS]

7101-51-1
[Synonyms]

DOPA-METHYLESTER
L-DOPA Methyl Ester
levodopa methyl ester
Methyl 3-hydroxy-L-tyrosinate
3-Hydroxy-L-Tyrosine methyl ester
L-Tyrosine, 3-hydroxy-, Methyl ester
(S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate
methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER
(S)-2-AMino-3-(3,4-dihydroxy-phenyl)-propionic acid Methyl ester hydrochloride
MelevodopaQ: What is Melevodopa Q: What is the CAS Number of Melevodopa Q: What is the storage condition of Melevodopa
[Molecular Formula]

C10H13NO4
[MDL Number]

MFCD00870911
[MOL File]

7101-51-1.mol
[Molecular Weight]

211.21
Chemical PropertiesBack Directory
[Boiling point ]

350.89°C (rough estimate)
[density ]

1.2545 (rough estimate)
[refractive index ]

1.5150 (estimate)
[storage temp. ]

2-8°C
[form ]

solid
[color ]

White
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P304+P340
[HS Code ]

2922500090
Hazard InformationBack Directory
[Description]

CHF-1301 was launched as an injection in Italy for the treatment of patients with Parkinson's disease, particularly those with complications in their clinical responses. CHF-1301 is the methyl ester of L-Dopa (levodopa), the immediate precursor of dopamine. Thus, this prodrug is more soluble in water at physiological pH, better absorbed and slowly transformed into levodopa in vivo; it consequently improves the duration of action and prevents the rapid fluctuations in response or involontary movements (dyskinesia) observed during chronic treatment with levodopa. In patients with a delayed effect of levodopa (on-phenomenon) or a severe resistance to L-Dopa (off-phenomenon), CHF- 1301 significantly improves the onset and the stability of the'response.
[Originator]

Chiesi Farmaceutici SpA (Italy)
[Definition]

ChEBI: Melevodopa is a tyrosine derivative.
[Brand name]

Levomet
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