| Identification | Back Directory | [Name]
1H-Pyrrole-2-carboxylicacid,3-cyano-,ethylester(9CI) | [CAS]
7126-44-5 | [Synonyms]
Ethyl 3-Cyanopyrrole-2-carboxylate
3-Cyan-2-pyrrolcarbonsaeure-ethylester
ethyl 3-cyano-1H-pyrrole-2-carboxylate
3-Cyano-1H-pyrrole-2-carboxylic acid ethyl ester
1H-Pyrrole-2-carboxylic acid, 3-cyano-, ethyl ester
1H-Pyrrole-2-carboxylicacid,3-cyano-,ethylester(9CI) | [Molecular Formula]
C8H8N2O2 | [MDL Number]
MFCD12756171 | [MOL File]
7126-44-5.mol | [Molecular Weight]
164.16 |
| Chemical Properties | Back Directory | [Melting point ]
92-93 °C | [Boiling point ]
130-140 °C(Press: 0.01 Torr) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
12.85±0.50(Predicted) | [Appearance]
Light yellow to light brown Solid |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of ethyl 3-cyano-1H-pyrrole-2-carboxylate from the compound (CAS:147299-51-2): a solution of 0.5 M ammonia (NH3) in dioxane (22 ml) was added slowly and dropwise to a solution of ethyl acetate (EtOAc, 30 ml) of 1b (1.62 g) at 60 °C. The reaction mixture was heated to reflux for 18 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was subsequently removed by rotary evaporation. The residue was purified by silica gel column chromatography to give the final light yellow solid product 88a (0.37 g). | [References]
[1] Patent: WO2016/7185, 2016, A1. Location in patent: Paragraph 00268; 00269 |
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Candia Thamtech Company Limited
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0371-86615086 18203638366 0371-86159066 13526786601 |
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www.chemicalbook.com/ShowSupplierProductsList15771/0_EN.htm |
| Company Name: |
SynAsst Chemical.
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021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
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