71306-36-0

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71306-36-0 Structure

Identification	Back Directory
[Name] 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-N-2-propen-1-yl-, hydrobromide (1:1)
[CAS] 71306-36-0
[Synonyms] Alinidine hydrobromide N-allyl-N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrobromide 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-N-2-propen-1-yl-, hydrobromide (1:1)
[Molecular Formula] C12H14BrCl2N3
[MOL File] 71306-36-0.mol
[Molecular Weight] 351.07

Chemical Properties	Back Directory
[storage temp. ] 4°C, away from moisture
[form ] Solid
[color ] White to light yellow

Hazard Information	Back Directory
[Uses] Alinidine (St-567) hydrobromide is a specific bradycardic agent. Alinidine hydrobromide reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine hydrobromide shows antiischemic and antiarrhythmic effects[1][2].
[References] [1] Snyders DJ, et al. Alinidine modifies the pacemaker current in sheep Purkinje fibers. Pflugers Arch. 1987;410(1-2):83-91. DOI:10.1007/BF00581900 [2] J L Challinor-Rogers, et al. Antiischemic and antiarrhythmic activities of some novel alinidine analogs in the rat heart. J Cardiovasc Pharmacol. 1997 Apr;29(4):499-507. DOI:10.1097/00005344-199704000-00011

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