| Identification | Back Directory | [Name]
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-N-2-propen-1-yl-, hydrobromide (1:1) | [CAS]
71306-36-0 | [Synonyms]
Alinidine hydrobromide
N-allyl-N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrobromide
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-N-2-propen-1-yl-, hydrobromide (1:1) | [Molecular Formula]
C12H14BrCl2N3 | [MOL File]
71306-36-0.mol | [Molecular Weight]
351.07 |
| Hazard Information | Back Directory | [Uses]
Alinidine (St-567) hydrobromide is a specific bradycardic agent. Alinidine hydrobromide reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine hydrobromide shows antiischemic and antiarrhythmic effects[1][2]. | [References]
[1] Snyders DJ, et al. Alinidine modifies the pacemaker current in sheep Purkinje fibers. Pflugers Arch. 1987;410(1-2):83-91. DOI:10.1007/BF00581900
[2] J L Challinor-Rogers, et al. Antiischemic and antiarrhythmic activities of some novel alinidine analogs in the rat heart. J Cardiovasc Pharmacol. 1997 Apr;29(4):499-507. DOI:10.1097/00005344-199704000-00011 |
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