| Identification | Back Directory | [Name]
Methyl 4-aminopyridine-2-carboxylate | [CAS]
71469-93-7 | [Synonyms]
CHEMPACIFIC 38133
methyl 4-aminopicolinate
4-aminopyridine-2-carboxylate
4-Aminopicolinic Acid Methyl Ester
Methyl 4-amino-2-pyridinecarboxylate
METHYL 4-AMINO-PYRIDINE-2-CARBOXYLATE
METHYL 4-AMINO-PYRIDINE-2-CARBOXYLIC ACID
4-aminopyridin-2-carboxylic acid methyl ester
4-amino-pyridine-2-carboxylic acid methyl est
4-Amino-2-pyridine carboxylic acid methyl ester
4-AMINO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
2-Pyridinecarboxylic acid, 4-amino-, methyl ester
2-Pyridinecarboxylicacid,4-amino-,methylester(9CI)
Methyl 4-aminopyridine-2-carboxylate ISO 9001：2015 REACH | [Molecular Formula]
C7H8N2O2 | [MDL Number]
MFCD00956000 | [MOL File]
71469-93-7.mol | [Molecular Weight]
152.15 |
| Chemical Properties | Back Directory | [Melting point ]
129-130° | [Boiling point ]
333.7±22.0 °C(Predicted) | [density ]
1.238±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
4.35±0.10(Predicted) | [color ]
White to Light yellow | [InChI]
InChI=1S/C7H8N2O2/c1-11-7(10)6-4-5(8)2-3-9-6/h2-4H,1H3,(H2,8,9) | [InChIKey]
YHOVYZINCVIRGK-UHFFFAOYSA-N | [SMILES]
C1(C(OC)=O)=NC=CC(N)=C1 |
| Safety Data | Back Directory | [RIDADR ]
UN2811 | [HazardClass ]
IRRITANT | [HS Code ]
2933399990 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white solid | [Uses]
Methyl 4-aminopyridine-2-carboxylate | [Synthesis]
Methyl 4-aminopyridine-2-carboxylate is synthesised using Methyl 4-azidopyridine-2-carboxylate as a raw material by chemical reaction. The specific synthesis steps are as follows:
4-Azido-pyridine-2-carboxylic acid methyl ester (3.9 g, 22 mmol, 1 eq) was solubilized in methanol (50 mL) and palladium 10 percent w on carbon (400 mg) was added. The mixture was stirred at room temperature over 4 bars pressure of hydrogen until completion of the reaction. The mixture was then filtered over a short pad of celite, and rinsed with methanol to afford the expected compound as a yellow powder (3.0 g, 90percent yield).
 | [References]
[1] Patent: US2013/102601, 2013, A1. Location in patent: Paragraph 0176
[2] Patent: US2013/102600, 2013, A1. Location in patent: Paragraph 0160; 0163 |
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