| Identification | Back Directory | [Name]
ETHANOL,2-[2-(2-PHENOXYETHOXY | [CAS]
7204-16-2 | [Synonyms]
Ph-PEG3
ETHANOL,2-[2-(2-PHENOXYETHOXY
Triethylene glycol monophenyl ether
2-[2-(2-Phenoxyethoxy)ethoxy]ethanol
Ethanol, 2-[2-(2-phenoxyethoxy)ethoxy]- | [Molecular Formula]
C12H18O4 | [MDL Number]
MFCD01099021 | [MOL File]
7204-16-2.mol | [Molecular Weight]
226.27 |
| Hazard Information | Back Directory | [Uses]
Ph-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [Biological Activity]
Ph-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [IC 50]
PEGs | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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