| Identification | Back Directory | [Name]
-Trimethoxyflavone | [CAS]
720675-74-1 | [Synonyms]
4'
6,2'
-Trimethoxyflavone
2-(2,4-dimethoxyphenyl)-6-methoxy-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-(2,4-dimethoxyphenyl)-6-methoxy- | [Molecular Formula]
C18H16O5 | [MOL File]
720675-74-1.mol | [Molecular Weight]
312.32 |
| Hazard Information | Back Directory | [Description]
Aryl hydrocarbon receptor antagonist (EC50= 0.9μM). Exhibits no short term agonist activity and no species or promoter dependence. | [Uses]
Biofilm inhibition activity of 6,2',4'-Trimethoxyflavone was studied. Potential therapeutic applications as an antibiofilm agent. | [in vivo]
6,2',4'-trimethoxyflavone-treated (5 mg/kg/day; i.p.) WT mice shows significantly decreased infarct volume, improved sensorimotor, and nonspatial working memory functions compared with their respective controls[3]. | Animal Model: | Male C57BL/6 wild-type (WT) mice, AHRcKO mice[3] | | Dosage: | 5 mg/kg/day | | Administration: | I.p. | | Result: | Both TMF-treated and AHRcKO mice attenuated acute cerebral infarction and functional impairments.
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https://www.bocsci.com |
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4008-099-669 |
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https://www.chemicalbook.com/ShowSupplierProductsList112975/0.htm |
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