| Identification | Back Directory | [Name]
2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- | [CAS]
721401-53-2 | [Synonyms]
Rivaroxaban L
Rivaroxaban-12
Decarbonyl Rivaroxaban
Rivaroxaban Impurities358
Rivaroxaban impurity P4D-P
Rivaroxaban Related Impurity G
Rivaroxaban Descarbonyl Impurity
Rivaroxaban descarbonyl imp(G) (pure)
Rivaroxaban Impurity G/ Rivaroxaban Descarbonyl Impurity
Rivaroxaban Descarbonyl Impurity(Crude)/ Rivaroxaban
Impurity G
Rivaroxaban Impurity 12/Decarbonyl Rivaroxaban/Rivaroxaban Impurity G
(R)-5-Chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
5-chloro-N-((2R)-2-hydroxy-3-{[4-(3-oxo-4-morpholinyl)-phenyl]amino}propyl)-2-thiophenecarboxamide
2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-
R)-4-chloro-N-(2-hydroxy-3-(4-(3-
oxomorpholino)phenylamino)propyl)cyclopen
ta-1,3- dienecarboxamide.
Imp. G:5-chloro-N-((2R)-2-hydroxy-3-{[4-(3-oxo-4-morpholinyl)-phenyl]amino}propyl)-2-thiophenecarboxamide
Rivaroxaban Impurity 12/
Decarbonyl Rivaroxaban/5-Chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-2-thiophencarboxamide | [Molecular Formula]
C18H20ClN3O4S | [MDL Number]
MFCD26227280 | [MOL File]
721401-53-2.mol | [Molecular Weight]
409.89 |
| Chemical Properties | Back Directory | [Melting point ]
>188°C (dec.) | [Boiling point ]
772.6±60.0 °C(Predicted) | [density ]
1.434±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.65±0.46(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic | [Major Application]
pharmaceutical small molecule | [InChI]
1S/C18H20ClN3O4S/c19-16-6-5-15(27-16)18(25)21-10-14(23)9-20-12-1-3-13(4-2-12)22-7-8-26-11-17(22)24/h1-6,14,20,23H,7-11H2,(H,21,25)/t14-/m1/s1 | [InChIKey]
OKMRQXXUAFSBCM-CQSZACIVSA-N | [SMILES]
[s]1c(ccc1C(=O)NC[C@H](O)CNc2ccc(cc2)N3CCOCC3=O)Cl |
| Hazard Information | Back Directory | [Uses]
Decarbonyl Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor. |
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