| Identification | Back Directory | [Name]
BAY-8002 | [CAS]
724440-27-1 | [Synonyms]
BAY-8002
BAY 8002 NEW
BAY8002;BAY 8002
2-[[2-Chloro-5-(phenylsulfonyl)benzoyl]amino]benzoic acid
Benzoic acid, 2-[[2-chloro-5-(phenylsulfonyl)benzoyl]amino]- | [Molecular Formula]
C20H14ClNO5S | [MDL Number]
MFCD05157149 | [MOL File]
724440-27-1.mol | [Molecular Weight]
415.85 |
| Chemical Properties | Back Directory | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO:83.19(Max Conc. mg/mL);200.05(Max Conc. mM)
Ethanol:28.0(Max Conc. mg/mL);67.33(Max Conc. mM) | [form ]
A solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
BAY 8002 is an inhibitor of monocarboxylate transporter 1 (MCT1; IC50 = 11.4 nM). | [in vivo]
BAY-8002 (80 and 160 mg/kg, p.o., twice daily, for more than 26 days) significantly inhibits tumor growth in Raji tumor-bearing mice[1]. | Animal Model: | Female NOD SCID mice bearing Raji cells (7-10 weeks old)[1] | | Dosage: | 80 and 160 mg/kg | | Administration: | P.O. twice daily for more than 26 days | | Result: | Inhibited tumor growth with no obvious body weight loss, but showed no effect on tumor regression. |
| [IC 50]
MCT1 | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
|