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72564-74-0

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72564-74-0 Structure

72564-74-0 Structure
IdentificationBack Directory
[Name]

MD 39-AM
[CAS]

72564-74-0
[Synonyms]

MD 39-AM
4-[Anilino]-2-(methylthio)pyrido[2,3-d]pyrimidine
Pyrido[2,3-d]pyrimidin-4-amine, 2-(methylthio)-N-phenyl-
2-(METHYLSULFANYL)-N-PHENYLPYRIDO[2,3-D]PYRIMIDIN-4-AMINE
[EINECS(EC#)]

604-604-1
[Molecular Formula]

C14H12N4S
[MOL File]

72564-74-0.mol
[Molecular Weight]

268.34
Chemical PropertiesBack Directory
[Boiling point ]

486.8±53.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[pka]

3.70±0.30(Predicted)
Hazard InformationBack Directory
[Uses]

MD-39-AM exhibits antihypertensive, diuretic and saliuretic activities with good in vivo pharmacokinetic characters[1][2].
[References]

[1] Monge A, et al., Diuretic and hypotensive activities of 4-anilino derivatives of 2-methylthiopyrido [2, 3-d] pyrimidines[J]. Arzneimittel-forschung, 1990, 40(11): 1230-1233.
[2] Pérez MJ, et al., Preliminary pharmacokinetics of a new pyridopyrimidine derivative. Arzneimittelforschung. 1991 Jun;41(6):640-4. PMID:1930354
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