| Identification | Back Directory | [Name]
1-STEAROYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE | [CAS]
7266-53-7 | [Synonyms]
18:0-18:2 PE
PE(18：0/18:2(9Z,12Z))
1-STEAROYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
1-STEAROYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE;18:0-18:2 PE
9,12-Octadecadienoic acid (9Z,12Z)-, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxooctadecyl)oxy]ethyl ester | [Molecular Formula]
C41H78NO8P | [MDL Number]
MFCD00674345 | [MOL File]
7266-53-7.mol | [Molecular Weight]
744.05 |
| Chemical Properties | Back Directory | [Boiling point ]
759.2±70.0 °C(Predicted) | [density ]
1.008±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
Solid | [pka]
1.17±0.50(Predicted) | [color ]
White to off-white | [InChIKey]
YDTWOEYVDRKKCR-KNERPIHHSA-N | [SMILES]
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O |
| Hazard Information | Back Directory | [Uses]
1-?Stearoyl-?2-?linoleoyl-?sn-?glycero-?3-?phosphoethanolamine is used in the mRNA combination therapy for treatment of cancer. | [Definition]
ChEBI: 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine is a 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl groups at positions 1 and 2 are specified as stearoyl and linoleoyl respectively. It is functionally related to a linoleic acid and an octadecanoic acid. It is a tautomer of a 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine zwitterion. | [Biological Activity]
Phosphatidylethanolamine (PE) is implicated in a numerous function like membrane fusioncell cycleautophagyapoptosisand cognitive function. 18:0-18:2 Phosphatidylethanolamine (PE) is one of the non-glycated PE in powdered milk. It is a beneficial source of fatty acid and plays an important role in immunological protection. |
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