| Identification | Back Directory | [Name]
MLS0315771 | [CAS]
727664-91-7 | [Synonyms]
MLS0315771
1,2-Benzisothiazol-3(2H)-one, 2-(2,5-dimethylphenyl)-6-fluoro-
2-(2,5-dimethylphenyl)-6-fluoro-2,3-dihydro-1,2-benzothiazol-3-one | [Molecular Formula]
C15H12FNOS | [MOL File]
727664-91-7.mol | [Molecular Weight]
273.33 |
| Hazard Information | Back Directory | [Uses]
MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM. | [Definition]
ChEBI: 2-(2,5-dimethylphenyl)-6-fluoro-1,2-benzothiazol-3-one is a member of benzothiazoles. | [storage]
Store at -20°C | [References]
[1] Sharma V, et al. Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts. J Biol Chem. 2011 Nov 11;286(45):39431-8. DOI:10.1074/jbc.M111.285502 |
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