ChemicalBook--->CAS DataBase List--->72778-00-8

72778-00-8

72778-00-8 Structure

72778-00-8 Structure
IdentificationBack Directory
[Name]

L-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID
[CAS]

72778-00-8
[Synonyms]

(R)-DTC-OH
L-5,5-Dimethylthiazolidine-4-carboxyl
L-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID
(R)-5,5-Dimethyl-4-thiazolidinecarboxylic Acid
(R)-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID
[Molecular Formula]

C6H11NO2S
[MDL Number]

MFCD00070264
[MOL File]

72778-00-8.mol
[Molecular Weight]

161.22
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

206°C dec.
[refractive index ]

[a]20D = - 149 ± 2 o (C=1 in water)
[storage temp. ]

2-8°C
[solubility ]

Dichloromethane, DMSO, Methanol
[form ]

Solid
[color ]

White to off-white powder
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Found to act on the cell membrane of tumour cells, possible causing a reverse transformation to normal cells through restoration of contact inhibition.
[Biological Activity]

L-5,5-Dimethylthiazolidine-4-carboxylic acid (DTC) is used as a proline analog with restricted conformation in studies on receptor bound conformational requirements for agonists and antagonists of angiotensin II (ANG II).
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
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