| Identification | Back Directory | [Name]
2-Butanol, 1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-, (2R,3R)-rel- | [CAS]
72795-26-7 | [Synonyms]
Zenidolol
2-Butanol, 1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-, (2R,3R)-rel- | [Molecular Formula]
C17H27NO2 | [MOL File]
72795-26-7.mol | [Molecular Weight]
277.4 |
| Hazard Information | Back Directory | [Uses]
Zenidolol (ICI-118551) is a selective β2 adrenergic receptor antagonist. Zenidolol inhibits β2-, β1- and β3-adrenergic receptor with Ki values of 0.7, 49.5 and 611 nM, respectively. Zenidolol can be used as an ocular hypotensive agent used for ophthalmic disease research[1]. | [References]
[1] Hoffmann C, et al. Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol. 2004 Feb;369(2):151-9. DOI:10.1007/s00210-003-0860-y |
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