72902-38-6

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72902-38-6 Structure

Identification	Back Directory
[Name] ANSAMITOCIN DERIV
[CAS] 72902-38-6
[Synonyms] PDM3 ANSAMITOCIN DERIV Mertansine Impurity 4
[Molecular Formula] C31H41ClN2O9
[MOL File] 72902-38-6.mol
[Molecular Weight] 621.12

Hazard Information	Back Directory
[Description] 20-O-Demethyl-AP3 is a secondary metabolite derived from Ansamitocin P-3, and Ansamitocin P-3 is a macrocyclic antitumor antibiotic exerting its therapeutic effects by inhibiting microtubules.
[Uses] 20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic[1].
[References] [1] Zhongfa Liu, et al. Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry. J Mass Spectrom. 2005 Mar;40(3):389-99. DOI:10.1002/jms.800

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