| Identification | Back Directory | [Name]
ARTEPILLIN C | [CAS]
72944-19-5 | [Synonyms]
ARTEPILLIN C
ArtepillinC,fromPropolis
ARTEPILLIN C500Mg, 1g, 5g.
3,5-Diprenyl-4-hydroxycinnamic acid
3,5-Diprenyl-4-hydroxy-trans-cinnamic acid
4-Hydroxy-3,5-bis(3-methyl-2-butenyl)cinnamic acid
3,5-Bis(3-methyl-2-butenyl)-4-hydroxy-trans-cinnamic acid
(E)-3-[4-Hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]propenoic acid
2-Propenoic acid, 3-[4-hydroxy-3,5-bis(3-methyl-2-buten-1-yl)phenyl]-, (2E)- | [Molecular Formula]
C19H24O3 | [MDL Number]
MFCD03456121 | [MOL File]
72944-19-5.mol | [Molecular Weight]
300.39 |
| Chemical Properties | Back Directory | [Melting point ]
98-99 °C | [Boiling point ]
447.7±40.0 °C(Predicted) | [density ]
1.092±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Acetonitrile: Soluble
DMSO: Soluble | [form ]
solid | [pka]
4.69±0.10(Predicted) | [color ]
Light yellow to yellow | [Cosmetics Ingredients Functions]
HUMECTANT
SKIN CONDITIONING | [InChI]
InChI=1S/C19H24O3/c1-13(2)5-8-16-11-15(7-10-18(20)21)12-17(19(16)22)9-6-14(3)4/h5-7,10-12,22H,8-9H2,1-4H3,(H,20,21)/b10-7+ | [InChIKey]
KABCFARPAMSXCC-JXMROGBWSA-N | [SMILES]
C(O)(=O)/C=C/C1=CC(C/C=C(/C)\C)=C(O)C(C/C=C(/C)\C)=C1 |
| Hazard Information | Back Directory | [Uses]
Artepillin C has gastroprotective, anti-inflammatory, antimicrobial, antioxidant, antitumor and choleretic activity. Artepillin C can be isolated from Brazilian green propolis[1][2]. | [References]
[1] Kobal MB,et al. Correlating Artepillin C cytotoxic activity on HEp-2 cells with bioinspired systems of plasma membranes. Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110943. DOI:10.1016/j.msec.2020.110943
[2] Beserra FP, et al. Artepillin C as an outstanding phenolic compound of Brazilian green propolis for disease treatment: A review on pharmacological aspects. Phytother Res. 2020 Sep 15. DOI:10.1002/ptr.6875 |
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