ChemicalBook--->CAS DataBase List--->73210-73-8

73210-73-8

73210-73-8 Structure

73210-73-8 Structure
IdentificationBack Directory
[Name]

Xamoterol hemifumarate
[CAS]

73210-73-8
[Synonyms]

Corwin
Carwin
Xamtol
XAMOTEROL
ICI-118587
Corwin:Xamtol
Xamoterol hemifumara
XAMOTEROL HEMIFUMARATE
XAMOTEROL HEMIFUMARATE SALT
QEDVGROSOZBGOZ-WXXKFALUSA-N
ICI 118587 HEMIFUMARATE SALT
N-(2-((2-hydroxy-3-(4-hydroxyphenoxy)propyl)aMino)ethyl)Morpholine-4-carboxaMide
1-(4-HYDROXYPHENOXY)-3-[2-(4-MORPHOLINOCARBOXAMIDO)ETHYLAMINO]-2-PROPANOL HEMIFUMARATE
bis[N-[2-[[2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]morpholine-4-carboxamide] fumarate
(+/-)-N-[2-[[HYDROXY-3-(4-HYDROXY)PROPYL]AMINO]ETHYL-4-MORPHOLINECARBOXAMIDE HEMIFUMARATE SALT
ICI 118587 hemifumarate salt, (±)-N-[2-[[Hydroxy-3-(4-hydroxy)propyl]amino]ethyl-4-morpholinecarboxamide hemifumarate salt
[EINECS(EC#)]

277-319-9
[Molecular Formula]

C36H54N6O14
[MDL Number]

MFCD00661104
[MOL File]

73210-73-8.mol
[Molecular Weight]

794.85
Chemical PropertiesBack Directory
[Melting point ]

168-169° (dec)
[storage temp. ]

Store at RT
[solubility ]

H2O: 10 mg/mL at 60 °C, soluble
[form ]

solid
[color ]

white
[CAS DataBase Reference]

73210-73-8
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Phenyl chloroformate-->XAMOTEROL HEMIFUMARATE
Hazard InformationBack Directory
[Description]

Xamoterol fumarate is a cardioselective partial beta-agonist, the first of its class to be developed for use in heart failure. The main advantage of xamoterol fumarate as a cardiotonic lies in the fact that its beta-blocking effect exerted during high sympathetic drive will protect the heart from overstimulation. It is claimed to be a viable but safer alternative to digoxin.
[Originator]

ICI (United Kingdom)
[Uses]

Stimulant (cardiac).
[Brand name]

Corwin
[Biological Activity]

β 1 -adrenoceptor-selective partial agonist (pA 2 values are 7.4-7.8 and 5.2-6.2 at β 1 - and β 2 -adrenoceptors respectively).
[storage]

Store at RT
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