| Identification | Back Directory | [Name]
2-[2-METHOXY-4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZO[4,5-B]PYRIDINE | [CAS]
73384-60-8 | [Synonyms]
Vardax
ar-l115bs
SULMAZOLE
5-b)pyridine,2-(2-methoxy-4-(methylsulfinyl)phenyl)-1h-imidazo(
2-(2-methoxy-4-(methylsulfinyl)phenyl)-3H-imidazo[4,5-b]pyridine
2-[2-METHOXY-4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZO[4,5-B]PYRIDINE
3H-Imidazo[4,5-b]pyridine, 2-[2-methoxy-4-(methylsulfinyl)phenyl]- | [EINECS(EC#)]
277-406-1 | [Molecular Formula]
C14H13N3O2S | [MDL Number]
MFCD00214085 | [MOL File]
73384-60-8.mol | [Molecular Weight]
287.34 |
| Chemical Properties | Back Directory | [Melting point ]
203-205° | [Boiling point ]
527.3±60.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
6?+-.0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure[1]. | [Definition]
ChEBI: An imidazopyridine that is 1H-imidazo[4,5-b]pyridine which is substituted at position 2 by a 2-methoxy-4-(methylsulfinyl)phenyl group. An A1 adenosine receptor antagonist, it was formerly used as a cardi
tonic agent. | [References]
[1] W J Parsons, et al. The new cardiotonic agent sulmazole is an A1 adenosine receptor antagonist and functionally blocks the inhibitory regulator, Gi. Mol Pharmacol. 1988 Apr;33(4):441-8. PMID:3128727 |
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